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These risks and uncertainties include, among others, those relating to our ability to obtain sufficient financing to continue as a going concern, the outcome of the review of the continued listing of our com stock on The Nasdaq Stock Market, our ability to develop and market diagnostic products, the level of third party reimbursement for our products, risks related to preclinical and clinical development of pharmaceutical products, including the identification of compounds and the completion of clinical outdoor storage sheds trials, our ability to form collaborative relationships, storage sheds than 8ft tall shed the effect of government storage sheds than 8ft tall shed regulation and the regulatory approval processes, market acceptance, our ability to obtain and protect intellectual property rights for our products, dependence on collaborative relationships, the effect of competitive products, industry trends and other risks identified in deCODE's filings with the Securities and Exchange Commission, including, without limitation, the risk factors identified in our most recent Annual Report on Form 10-K and any updates to those risk factors filed from time to time in our Quarterly Reports on Form 10-Q or Current Reports on Form 8-K. DeCODE Study Shows Complex Interplay of the Human wooden storage shed with car port Biological Clock With Height, Weight and Disease
Reykjavik, ICELAND, / - / -- In a paper published
today in the online edition of Nature Genetics, scientists from deCODE genetics (Nasdaq:DCGN) and academic colleagues from Iceland, Denmark and the Netherlands present the discovery of single letter variations in the sequence of the human genome (SNPs) that influence the shed kits age of girls carport shed roof kit at menarche, the first menstrual period. Visit us on the web at on our diagnostics site for our pioneering personal genome analysis service and new focused disease scans, integrating the genetic variants included in these tests and those linked to another twenty com diseases, as well as for our new deCODEme Cardio(TM) and deCODEme Cancer(TM) scans, and on our blog at.
AAM is of interest not only because it heralds the beginning of a woman's reproductive life, but because it is also linked with susceptibility sheds for sale to disease later in plastic sheds life. Indeed, looking at height measurements from 38,000 Icelandic women, those carrying these SNPs were 0.3 cm taller per copy carried. Through the analysis of more than 300,000 SNPs across the genomes of more than 15,000 Icelandic women, and confirmed through genotypic analysis of some 10,000 Danish and Dutch women, the deCODE team identified two com SNPs on chromosome 6q21 that are associated with between one and two months later AAM per copy carried. This was encouraging, as last year deCODE had linked the same SNPs to greater adult height, and increased aldult height has been shown to correlate with later AAM. Age at menarche (AAM) is influenced by both genetic and door handle for storage shed environmental factors, though the SNPs reported today are the first genetic factors to be found. This is in keeping with the fact that the 6q21 variants also confer greater adult height in men, and also suggests that these SNPs should be involved in the onset of puberty in boys as well.
The paper, "Genome-wide association study identifies sequence variants on 6q21 associated garden buildings with age at menarche," is published in the online edition of Nature Genetics, at /ng, and will be published in an upcoming print edition of the journal. Based upon these discoveries deCODE has brought to market a growing range of DNA-based tests for gauging risk and empowering prevention of com diseases.
Through its CLIA-registered laboratory, deCODE offers deCODE T2(TM) for type 2 diabetes; deCODE AF(TM) for atrial fibrillation and stroke; deCODE plastic corner frames for garden shed frame MI(TM) for heart attack; deCODE ProstateCancer(TM) for prostate cancer; deCODE Glaucoma(TM) for a major type of glaucoma; and deCODE BreastCancer, for the com forms of breast cancer. The deCODE team also demonstrated that several known genetic variants linked to overweight and obesity also correlated with earlier AAM. DeCODE is a bio-pharmaceutical company developing drugs and DNA-based tests to improve the treatment, diagnosis and prevention of com diseases.
Later AAM increases risk of osteporosis.
DeCODE undertakes no obligation to update or alter these forward-looking statements as a result of new information, future events or otherwise.. We plan to incorporate the most interesting of today's findings into our deCODEme(TM) personal genome analysis service," shed door handles handle said Bobbee Stefansson, CEO of deCODE and senior author on the paper. Its lead therapeutic programs, which leverage the company's expertise in chemistry and structural biology, include DG041, an antiplatelet compound being developed for the prevention of arterial thrombosis; DG051 and DG031, compounds targeting the leukotriene pathway for the prevention of heart attack; and DG071 and a platform for other PDE4 modulators with therapeutic applications in Alzheimer's disease and other conditions. DeCODE is delivering on the promise of the new genetics(SM). These forward-looking statements are subject to a number of risks and uncertainties that could cause water shed actual results, and the timing of events, to differ materially from those described in the forward-looking statements.
Any statements contained in this presentation that relate to future plans, events or performance are forward-looking statements within the meaning of the Private Securities Litigation Reform Act of 1995.
But we have also been able to use them to confirm that overweight and obesity is linked to earlier AAM, and to suggest that later AAM contributes to greater height. DeCODE is a global leader in human genetics, and has identified key variations in the genome (SNPs) conferring increased risk of major public health challenges from cardiovascular disease to cancer. "The findings presented today are evidence of how our approach of bringing together vast amounts of genetic and health information can shed light on the processes driving complex human traits.
Furthermore it appears that it is AAM that is having the impact on height, and not the other way around. The next step in this work is to look at how these and other new genetic factors linked to the timing of the reproductive cycle may be used to predict and prevent disease. These SNPs offer a first step toward understanding the genetic component of AAM, and probably the timing of the onset of puberty in boys as well. Obesity in particular is linked to earlier AAM, and earlier AAM is in turn associated with risk of breast, ovarian and endometrial cancers.
